Basics of a career in genomics research

From agriculture to climate science, genomics is driving innovations 
| Photo Credit: Freepik

Imagine a career where your everyday work could impact the lives of millions of people. Were you curious to know more about genomics during COVID-19? The pandemic was a big reminder of the role and importance of genomics and its potential to solve some of the most pressing issues of our time. As we stand on the brink of unprecedented breakthroughs in healthcare, students and young professionals have a unique opportunity to shape the future by entering the field of genomics.

Genomics is not just an academic pursuit; it is a transformative field with the power to solve some of humanity’s greatest challenges. It is at the intersection of Biology, Data Science, and technology; a trifecta of skills that defines the future of healthcare. It is not just about understanding genes but about leveraging that knowledge to address critical issues like cancer, rare genetic disorders, and even infectious diseases like COVID-19. Its applications go beyond healthcare. From agriculture to climate science, genomics is driving innovations such as genetically engineered crops that withstand harsh conditions and microbiomes that promote environmental sustainability.

What it involves

Genomics research focuses on studying an organism’s entire DNA, including all its genes, to uncover insights into health, disease, and evolution. It involves:

Genome mapping: Sequencing DNA to identify the location and function of genes

Genetic variation: Exploring mutations and differences that influence traits and disease risks

Precision medicine: Using genomic data to personalise diagnostics and treatments

Functional genomics: Understanding how genes interact to regulate biological processes

Epigenomics: Investigating how gene activity is modified by environmental or chemical factors

Education and skills

Genomics research typically requires a Bachelor’s degree in Biotechnology, Genetics, Molecular Biology, or related field and a Master’s degree for specialised roles in genomics, bioinformatics, or clinical applications. A Ph.D. is essential for leadership positions in research and academia.

Aspirants require a blend of technical, analytical, and soft skills. Additional certifications in bioinformatics, next-generation sequencing (NGS), or clinical genomics (e.g., ACMG, NSGC) and technical expertise in CRISPR, data analysis tools like R and Python, and laboratory techniques such as PCR are crucial. Strong data analysis skills to interpret large datasets and detect patterns are essential, along with interdisciplinary knowledge combining Biology, Computer Science, and Statistics. Effective communication and is vital to write research papers, collaborate with teams, and explain findings to non-specialists.

Prospects

Genomics offers diverse career paths. Junior and senior research fellows (JRF/SRF) and PhD researchers focus on lab work, experiments, and scientific advancements. Lab technicians play a vital role in maintaining operations and conducting key experiments. Field application scientists support tools like Illumina machines through troubleshooting and optimisation. Scientific liaisons bridge the gap between researchers and clinicians, translating genomic insights into practical applications. Additionally, business development professionals drive collaborations and market growth, leveraging their understanding of genomics to expand industry impact.

Governments and private sectors worldwide are investing heavily in genomics and biotech and the market is projected to grow exponentially, creating an array of career opportunities from research and development to entrepreneurship and policy-making. In India, initiatives like Startup India, Make in India, and increased focus on healthcare innovation offer fertile ground for aspiring professionals. There is a need for talented and passionate professionals who are pushing the boundaries of what is possible.

Genomics is transforming healthcare by enabling earlier disease detection, personalised therapies, and targeted drug development. It also drives innovation in agriculture, biodiversity conservation, and environmental science, making it a cornerstone of 21st-century research.

The writer is CEO and Co-Founder, 4baseCare.

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